A general procedure for calculating the ionization equilibrium constants of polybasic acids

Abstract

This program applies the Newton-Gauss-Marquardt method and the principle of least squares to solve the difficulty of calculating the ionization equilibrium constants of each overlapping step using polybasic acid potentiometric titration data. The results given by this program written in BASIC language are close to the literature values and the values obtained by the Rossotti method. This method does not add any omissions, so it should be better than the Rossotti method in dealing with multiple acid dissociation constants of polybasic acids.